3-Sulfamoylphenylboronic Acid Pinacol Ester

3-Sulfamoylphenylboronic Acid Pinacol Ester - Names and Identifiers

Name	Benzenesulfonamide, 3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-
Synonyms	3-Boronobenzenesulfonamide,pinacol ester 3-Sulfamoylphenylboronic Acid Pinacol Ester BENZENESULFONAMIDE-3-BORONIC ACID PINACOL ESTER 3-aMinosulfonyl-phenylboronic acid pinacol ester 3-(tetramethyl-1,3,2-dioxaborolan-2-yl)benzene-1-sulfonamide Benzenesulfonamide, 3-(4,4,5,5-tetramethyl-1,3,2-dioxaborola... 3-(4,4,5,5-tetraMethyl-1,3,2-dioxaborolan-2-yl)benzenesulfonaMide Benzenesulfonamide, 3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-
CAS	486422-08-6

3-Sulfamoylphenylboronic Acid Pinacol Ester - Physico-chemical Properties

Molecular Formula	C12H18BNO4S
Molar Mass	283.15
Density	1.24±0.1 g/cm3(Predicted)
Boling Point	447.1±47.0 °C(Predicted)
pKa	10.04±0.60(Predicted)
Storage Condition	2-8°C

3-Sulfamoylphenylboronic Acid Pinacol Ester - Introduction

Benzenesulfonamide, 3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-is an organic compound with the chemical formula C13H17BNO4S. It is a white to pale yellow crystalline powder with low solubility. The following is a description of the properties, uses, preparation and safety information of the compound:

Nature:
-Appearance: White to light yellow crystalline powder.
-Solubility: The substance has low solubility in water and is soluble in organic solvents such as dimethyl sulfoxide (DMSO) and dichloromethane.
-Melting point: about 141-146 ℃.

Use:
-As an intermediate in organic synthesis: This compound can be used as a raw material or intermediate in organic synthesis for the synthesis of other compounds.
-Used in drug research: It can be used as research materials in anti-cancer drugs or other related fields in drug research.

Preparation Method:
Benzenesulfonamide-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-is synthesized as follows:
1. benzenesulfonamide (with serial number) is reacted with 3-(4,4,5,5-tetramethyl -1,3, 2-dioxobutyl) borate in a suitable organic solvent.
2. The product obtained is purified by crystallization or column chromatography to obtain the desired product.

Safety Information:
-Good laboratory practices should be followed, including the wearing of personal protective equipment (e. g., lab gloves, goggles).
-The compound may be toxic to humans and should be avoided from skin contact, inhalation or ingestion.
-When using, please refer to the information in the relevant safety data sheet (SDS) and chemical label, and store and handle the compound properly.

Last Update：2024-04-09 02:00:46